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Flushing after wine, unexplained hives, sinus headaches… many “mystery allergies” are really histamine intolerance (HIT)—an overload of histamine plus sluggish detox enzymes, mainly diamine oxidase (DAO). A Functional-Medicine lens shows HIT is rarely “just genes.” Gut dysbiosis, SIBO, nutrient gaps, mast-cell overdrive, hormones, meds, mould toxins and stress all pile on. This icon-guided playbook breaks down root causes 🔍, low-histamine meal design 🥑, DAO + vitamin co-factors 💊, probiotic picks 🦠, quercetin stacks 🍏, vagus-calming hacks 🧘‍♀️ and SIBO/gut repair 🔧—with peer-reviewed research to back every step.

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Dr. Alessio Fasano has shown in countless studies that gluten does affect everyone.

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Dr. John Nieters, DAOM, L.Ac, M.Sc. CFMP